Huff hurts knee during perfect game celebration
An MRI performed Thursday revealed the extent of the damage.
"He's got a pretty good bruise in the right knee," Giants manager Bruce Bochy said. "He's going to lose some time, and he was going to have some at bats in the American League parks. It's a bad break for him and for us."
Cain threw the first perfect game in Giants history in a 10-0 win over the Houston Astros on Wednesday night - the second perfect game and fifth no-hitter in the majors this season.
Huff, a top candidate for designated hitter when the Giants visit Seattle for an interleague series this weekend, landed on his knee as he jumped over the railing and had to be helped off the field.
Huff is hitting only .120 in 19 games since being activated from the disabled list.
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