Posted: Thursday September 6, 2012 1:01PM ; Updated: Friday September 7, 2012 12:03PM
Andrew Perloff
Andrew Perloff>INSIDE THE NFL

Bet On It: Week 1 predictions

Story Highlights

Ffive rookie starting QBs will all lose; Russell Wilson has the best chance to win

LeSean McCoy will have a field day against the Browns' depleted run defense

Peyton Manning will have a big yardage day in Week 1, but Drew Brees won't

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Maurice Jones-Drew
Jaguars coach Mike Mularkey said Maurice Jones-Drew would be a third-down back in Week 1, but don't count on that.
Phelan M. Ebenhack/AP

Each week we'll take our best shot at the predictions beyond the game predictions.

Here we go for Week 1, minus the Cowboys' 24-17 win over the Giants (which I totally would have nailed, by the way).

1. The NFC North will go 4-0 in Week 1.

Coming off a 3-13 season, the Vikings appear to be the riskiest part of this equation. But since Minnesota hosts the Jaguars, this is the week to go all in on the NFC North. The Packers face a stiff challenge against the Niners, but it's at Lambeau. You have to feel confident about the Bears hosting the Colts and the Lions hosting the Rams.

2. The five starting rookie quarterbacks will go 0-5 in Week 1.

Last season Cincinnati's Andy Dalton beat Cleveland in Week 1 and Carolina's Cam Newton lost to Arizona. This year, Indy's Andrew Luck (at Chicago), Washington's Robert Griffin III (at New Orleans), Cleveland's Brandon Weeden (vs. Philadelphia) and Miami's Ryan Tannehill (at Houston) are all underdogs. Russell Wilson is the one to watch with this prediction. Wilson's Seahawks are favored at Arizona, but these teams split two close games last year and it's going to be tough to get an early divisional win on the road.

3. Eagles running back LeSean McCoy will total over 150 yards from scrimmage against Cleveland.

McCoy has to be salivating at the thought of facing the 30th-ranked run defense in 2011, and one that will be missing defensive tackle Phil Taylor. Even if the Browns find a way to slow down the run, McCoy is dangerous in the passing game because the defense has to turn its attention downfield to receivers Jeremy Maclin and DeSean Jackson.

4. Jaguars running back Maurice Jones-Drew will get at least 15 touches.

Jacksonville coach Mike Mularkey is probably still a bit upset with MJD after his lengthy holdout, but this is a winnable game against the Vikings. By Sunday afternoon, he'll have forgotten about that "third-down back" talk and make sure Jones-Drew gets carries and receptions.

5. Jets quarterback Tim Tebow scores a touchdown.

It's a bold prediction considering the Jets went most of the preseason without getting in the end zone, and Tebow wasn't responsible for the one they did score. But New York offensive coordinator Tony Sparano was keeping his real game plan close to the vest, and the Jets' offense will be more effective against a Bills defense that looks better on paper, but still has something to prove.

6. Broncos quarterback Peyton Manning throws for over 300 yards and at least two interceptions.

Manning can have success in the air against a traditionally tough Pittsburgh pass defense that will be missing Ryan Clark. The best way to beat Pittsburgh's D is to spread out the offense, so Manning will test them that way. But Peyton still has to prove how healthy his arm is after making some questionable throws during the preseason. Look for Pittsburgh's defenders to jump routes to try to make a big play. This could be the story of Manning's season -- lots of yards, but more interceptions than normal.

7. Steelers wide receiver Antonio Brown will have over 90 receiving yards.

Fellow Pittsburgh receiver Mike Wallace is still learning a new offense and the Steelers' running game isn't settled yet. Ben Roethlisberger is comfortable with Brown, who got a big contract in the offseason, and will rely on him when the Broncos' pass rush is bearing down.

8. Saints quarterback Drew Brees throws for fewer than 342 yards against the Redskins (his 2011 per game average).

Everyone expects the Saints to be extra motivated in Week 1 because of their emotional offseason. They won't need to get into full gear for this contest against the Redskins, even though Washington will be missing starting safeties Brandon Merriweather (injury) and Tanard Jackson (suspension). Washington will try to slow down the game with a conservative attack, and the Saints should try to establish the running game. The Redskins ranked 12th against the pass last year and can get after the QB, while they were just 18th against the run.

9. Houston Texans will have at least five sacks on Sunday.

The Texans' pass rush was strong last season and could be even better this year with rookie Whitney Mercilus in the mix. Connor Barwin, Brooks Reed and J.J. Watt have to be excited to chase the rookie Tannehill. If they can stop Miami running backs Reggie Bush and Daniel Thomas and put Tannehill in obvious pass situations, the Texans' front seven will cause total mayhem.

10. Carolina runs for over 175 yards against the Buccaneers.

Even with Jonathan Stewart iffy because of a preseason ankle injury, the Panthers will gash a defense they ran all over last year. Carolina amassed 433 yards on the ground in 38-19 and 48-16 wins over the Bucs last season. New Tampa Bay coach Greg Schiano may not have enough talent to fix this unit immediately. If Stewart can't contribute, new addition Mike Tolbert can help in both the running and passing games. Cam Newton ran for 119 yards on 20 carries last season against the Bucs.

You can rip me for not making bold enough calls, or you can rip me for being wrong -- but not both. Hit me @andrewperloff with your bold predictions and to disagree with mine.

 
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