LOUISVILLE, Kentucky (Ticker) -- Fifteenth-ranked Louisville seeks to end its regular season on a positive note Saturday when it hosts Charlotte in a Conference USA matchup at Freedom Hall.
The Cardinals had won 18 consecutive games and seemed to have control of the American Division before losing five of their last seven games. They have fallen three games behind first-place Marquette and are just one ahead of third-place Cincinnati.
Louisville's struggles continue with a 79-76 overtime loss at DePaul on Wednesday.
Freshman Taquan Dean scored 16 points and Reece Gaines added 15 for the Cardinals (20-6, 10-5 American), who were heavily outrebounded, 48-28, and made just 9-of-31 3-pointers.
Despite its recent struggles, Louisville is still off to the best start since the 1996-97 season, when it went 26-9 and made an appearance in the NCAA Tournament quarterfinals.
The Cardinals avoided a three-game home losing streak with a win over East Carolina on March 1. They are 10-2 at Freedom Hall this season.
Charlotte (13-14, 8-7) had its three-game winning streak snapped with a 50-39 loss at Saint Louis on Wednesday.
Eddie Basden and Demon Brown scored nine points apiece for the 49ers, who shot just 28 percent from the floor and were held to a season low in points.
Brown, the nation's leading 3-point shooter, made just 3-of-15 shots, including 3-of-13 from beyond the arc. He is just 4-of-24 from the floor in his last two games.
Despite his slump, Brown has made 132 3-pointers this season, tying Mississippi Valley's Timothy Pollard and Duke's Jason Williams for seventh place all time. He is just five shy of tying Dennis Scott of Georgia Tech for fourth place.
The 49ers have lost just two of their last seven games and are tied with Saint Louis for fourth place in the American Division.
Louisville has won the last two meetings with Charlotte, which has won six of the last nine games between the teams and 10 of the last 14. The Cardinals and 49ers have split 28 meetings all time.