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AMES, Iowa (Ticker) -- Nick Collison had quite a homecoming.

Collison scored a season-high 31 points to lead No. 14 Kansas to its seventh straight win, an 83-54 rout of Iowa State in the Big 12 Conference opener for both teams.

Collison is a native of Iowa Falls, Iowa, about 30 miles from here. He and fellow Iowan Kirk Hinrich left their home state to play at neighboring Kansas, which made many folks unhappy.

Last season, Collison and Hinrich got their first win in their home state. In this one, Collison took charge, making 11-of-15 shots and leading Kansas to an easy win.

Keith Langford added 15 points and Aaron Miles 13 for the Jayhawks (10-3), who raced to a 22-2 lead and never looked back.

Kansas played for the first time without starting forward Wayne Simien. The sophomore dislocated his right shoulder in the first half of Saturday's rout of Missouri-Kansas City and there is no timetable for his return.

Jared Homan had 14 points and 10 rebounds for the Cyclones (10-2), who had a five-game winning streak snapped.

Collison scored eight points and Miles seven in the early surge, which Hinrich capped with a basket at the 11:54 mark. Marcus Jefferson finally made Iowa State's first basket 33 seconds later.

Collison scored 12 points and Miles 11 in the first half, when the Jayhawks shot 50 percent (14-of-28) and held the Cyclones to 29 percent (9-of-31), opening a 39-21 lead.

Iowa State got no closer than 47-32 in the second half. Kansas led by as many as 31 points.

Jeff Graves started for Simien and had seven points and 10 rebounds.

Jake Sullivan scored 13 points for Iowa State, which shot just 37 percent (22-of-60), including 1-of-12 from 3-point range.

Iowa State's Larry Eustachy remains the only active Big 12 coach with a winning record vs. Kansas, falling to 5-4.