CHAMPAIGN, Illinois (Ticker) -- Playing from behind eventually took its toll on Purdue.
Brian Cook scored 22 points on 6-of-10 shooting as 15th-ranked Illinois bounced back from a pair of losses with a 75-62 Big Ten Conference victory over Purdue, which missed its final 14 shots.
Purdue (11-4, 3-1 Big Ten) had its last lead at 7-6 before the Fighting Illini went ahead by as many as 12 points in the first half. The Boilermakers used a 10-2 burst to get within 33-29 at halftime and twice got within a point early in the second half.
But Illinois regrouped and opened a 57-49 lead on a dunk by Nick Smith with eight minutes to go.
Purdue again did not fold, running off seven straight points and climbing within 57-56 on two free throws by Willie Deane with 6:46 remaining. But the Boilermakers did not make a basket the rest of the way.
Luther Head chipped in 15 points, freshman Dee Brown scored 13 and freshman Deron Williams collected 11, seven rebounds and seven assists for Illinois (12-3, 3-2), which was swept by Iowa and Indiana on its recent road trip.
Williams made both of his 3-pointers and was 3-of-6 from the field after going 1-of-13 in the previous two games.
Deane made just 3-of-11 shots but finished with 14 points to lead Purdue, which had a six-game winning streak snapped. Kenneth Lowe chipped in 13 but was the only other player in double figures for the Boilermakers, who shot under 29 percent in the second half (8-of-28).
The Illini connected at 50 percent (13-of-26) after halftime and held Purdue without a basket for the final 6:46.
After Illinois scored the game's first four points, Brandon McKnight made a couple of layups to give the Boilermakers their last lead. But the Fighting Illini answered with a 13-2 run as Head drilled two of his three 3-pointers for a 19-9 cushion seven minutes in.
Trying for its first 4-0 start in Big Ten play since 1995-96, Purdue shot under 33 percent (19-of-58), going 3-of-16 from the arc.
Illinois has won four of the last five meetings in the series, including two in a row at home.