Cuffle scored 25 points and limited Korver, a national Player of the Year candidate, to just five as Evansville upset No. 9 Creighton, 74-66, in a Missouri Valley Conference matchup.
Dan Lytle and Lucious Wagner added 15 points apiece for the Purple Aces (6-9, 2-4 MVC), who avenged a 93-56 loss at Creighton (16-2, 7-1) on January 15.
In that contest, Korver nailed nine 3-pointers en route to a 31-point night. But in this one, Korver shot just 1-of-12, including 0-of-7 from the arc.
"We weren't going to let Korver beat us," Cuffle said. "I tried to take Korver out of their offense and make other guys on their team beat us."
"The toughness and concentration that Clint Cuffle showed in defending Kyle Korver made the difference tonight," Evansville coach Steve Merfeld said.
The Bluejays led the back-and-forth contest, 61-60, before Cuffle answered with a layup with 2:35 remaining to give the Purple Aces the lead for good.
"We focused on making this game a series of four-minute segments," Merfeld said. "We played each segment like it was the last four minutes of the game."
Mike Grimes scored 14 points and DeAnthony Bowden added 11 points for the Jays, who were seeking their first 17-1 start in school history.
Evansville shot 56 percent (28-of-50), including 57 percent from the arc (8-of-14). The Purple Aces outscored the Bluejays in the paint, 38-26.
"We ran our offense really well against Creighton's pressure defense and that got me open for some easy buckets inside," said Cuffle, who made 9-of-14 shots. "This is a great stepping stone for our program. It gives us faith that we can win anytime we play."
Creighton was limited to 38 percent (22-of-58) shooting overall and 25 percent from the arc (5-of-20).
"We didn't shoot well and that took a little energy away from us but Evansville really played well," Creighton coach Dana Altman said. "They hit a lot of big baskets and they simply outplayed us."
The Purple Aces won the battle of the boards, 34-31, and had 21 assists to the Bluejays' seven.
It was the third time in four seasons that Creighton routed Evansville in Omaha before losing to the Purple Aces on the road.
"We've lost a little bit of our hunger," Altman said. "We didn't have the same passion for the game that Evansville did tonight. Evansville's energy level went way up and ours did not."