PITTSBURGH (Ticker) -- "March Madness" arrived at Duquesne a couple of days early.
Anthony Myles hit a follow shot with 0.7 seconds left in regulation and 13th-ranked Xavier held off Duquesne at the frenzied end of overtime for an 80-78 Atlantic 10 victory.
After Xavier's A-10 Player of the Year candidate David West was unable to muscle in a layup in the final seconds of regulation, Myles swept the boards and sank a putback to forge a 73-73 tie.
With the Dukes trailing by two points with 17 seconds left in the extra session, Jimmy Tricco missed a 3-pointer and Duquesne squandered several chances to convert the rebound, including a layup by Brad Midgley that rolled off the rim.
The Dukes (9-18, 3-11 A-10 West) retained possession when the ball went out of bounds with 3.7 seconds left, but Kevin Forney missed a 3-pointer and the double-digit underdogs' upset bid fell just short.
"We ran a play for a three we've worked on all season," Tricco said. "It worked in Florida (in December). It didn't work today."
West finished with 19 points, eight rebounds and four assists and Lionel Chalmers added 17 points for the Musketeers (21-4, 12-1), who won their 12th straight game.
"I knew this was going to be a tough place to play, this was a huge game for their seniors," Xavier coach Thad Matta said. "We weren't very good tonight."
Forney scored 18 off the bench for the Dukes, who have lost 10 of their last 12.
Trailing 48-46, the Dukes went ahead when freshman Bryant McAllister followed Midgley's two free throws with a jumper at the 14:52 mark of the second half.
Duquesne remained on top until Chalmers' nailed a 3-pointer with 64 seconds left in regulation to give the Musketeers a 69-68 lead.
The Dukes took a three-point advantage as Elijah Palmer and Ron Dokes each hit two free throws, the latter with 24.3 seconds left. But West sank a layup and McAllister hit only 1-of-2 from the line, setting up Myles' heroics.
Freshman Dedrick Finn scored 16 points, Romain Sato had 15 points, eight rebounds and seven assists and Myles registered 13 points and eight boards for Xavier, which improved to 7-0 on the road in the A-10 and remained one-half game ahead of second-place Dayton in the West.
The Musketeers led the entire overtime period despite going without a basket over the final 3:21.
Duquesne had chances to take advantage. Following a free throw by Sato with 2:18 left that gave Xavier an 80-77 lead, Forney hit 1-of-2 from the line. Finn's two misses left the door open for the Dukes, but they were unable to capitalize.
"This was a very difficult loss," Duquesne coach Danny Nee said. "I thought we played as hard as we could. We had chances, we just couldn't close it out. It was a heck of a basketball game."
Palmer scored 17 points and Dokes collected 15 and seven rebounds as Duquesne lost for the sixth time in the past seven at home.
The Dukes shot 57 percent in regulation but made just 2-of-11 shots in overtime.
Xavier twice led by seven points in the first half, but the Dukes were able to pull even at halftime, 39-39.