Schaub has had two excellent games thus far this season. He posted an average statistical game against the Raiders, but that was a product of Houston's second-half dependence on the run with a lead. This one figures to be a shootout and Schaub is a definite No. 1 option.
Slaton hasn't had a 100-yard rushing game yet this season and will be hard-pressed to do so against a Cardinals' defense that's allowing less than 80 rushing yards a game. He had two big TDs against the Raiders last week and is beginning to prove why he was a consensus first-round fantasy pick.
Like the Daft Punk song, Johnson is Bigger. Faster. Stronger. He was only targeted twice in the second half vs. the Raiders (two catches, 66 yards), but is likely to have a big game in this shootout. He's an elite fantasy wideout and a must-start every week.
Walter only caught one pass for 41 yards against the Raiders but, as mentioned, Schaub put it away during the second half. He could have a good game here as the teams run it up and down the field. Walter is a decent, high-end No. 3 option, perhaps a No. 2 given his considerable upside.
Like the rest of Schaub's targets, Daniels numbers (2 catches, 48 yards) suffered because of the big first half against Oakland. He's a good tight end and a trusted target. Maybe he's not at the elite level -- ninth among TEs with 17 catches on the year -- but a solid start every week.
Warner's had a slight case of the picksies this year, throwing four interceptions to go along with his four touchdowns. Houston's been decent against the pass (10th in yardage allowed), but those numbers may be inflated because they played the inept Raiders. He's a must-start No. 1 QB in this battle of high-octane offenses.
Like his namesake from the Police Academy films, Hightower will loom large in this game. Houston has allowed 165 yards a game on the ground, and Hightower will likely take advantage of that to the tune of his second career 100-yard game.
Old Fitzie hasn't gone off yet. He's gotten in the end zone twice, but hasn't had a 100-yard game yet. It's coming this weekend. Look for him to be targeted repeatedly, as the 1-2 Cards try to recapture the magic that took them to the Super Bowl last season.
Like his bookend wideout, Boldin has yet to hit his stride this year. He had his best game of the season before the bye week against Indy with six catches for 83 yards and a TD. He's a No. 1 fantasy option even if he isn't the No. 1 option on his own team.
Breaston led the Cards in yards against the Colts with 94. It's not often that a No. 3 WR is a viable fantasy option, but Breaston certainly is. He may end up being the only No. 3 WR to go for 1,000 yards.