Arrowhead Stadium | Monday, September 13 | 10:15 p.m. EST (ESP)
Pick: Chargers 27, Chiefs 10
300 pass yards, 2 pass TD, 0 rush TD, 1 INTRivers averaged 285 yards in two games against the Chiefs last season and tossed five touchdown passes in those contests. Though top wideout Vincent Jackson won't play, Rivers is, as always, a strong option.
1 rec, 10 rec yards, 75 rush yards, 1 rush TDThe Chiefs finished 31st in rush defense last season, so Mathews should find plenty of holes -- and reach the end zone -- in his NFL debut.
4 rec, 35 rec yards, 15 rush yards, 0 rush TDSproles will play a complementary role in the Chargers' backfield and probably won't see enough carries to make much of an impact in Week 1. Expect a heavy dose of Ryan Mathews.
6 rec, 90 yards, 1 TDFloyd will be the Chargers' number one receiver until Vincent Jackson returns, so expect him to see plenty of targets from Philip Rivers. Floyd's lone touchdown last season came against Kansas City.
3 rec, 65 yardsNaanee could benefit from the attention paid to the Chargers' other skill players and is a sneaky Week 1 option against a young Chiefs secondary.
8 rec, 100 yards, 1 TDGates has scored 11 times in 12 career games against the Chiefs and is good bet for big Week 1 numbers as Philip Rivers' top option in the passing game again.
3 PATs, 2 FGsKaeding averaged 12 points per game against the Chargers last season and is a good bet to reach double figures again.
4 sacks, 2 INT, 0 Fumbles, 0 TDThe Chargers gave up just three total touchdowns in two games against Kansas City last season. Kansas City may be able to score a little more this time around, but the Chargers should be able to record a couple sacks and force a turnover or two.
150 pass yards, 1 pass TD, 10 rush yards, 2 INTCassel's first chance to test out his new weapons comes against last year's No. 11 pass defense. Opening the season at Arrowhead Stadium on Monday Night Football should give the Chiefs a lift, but Cassel must still prove 2008 wasn't an aberration.
2 rec, 15 rec yards, 60 rush yardsThomas Jones will steal some carries, but Charles is the more talented back and should get the bigger chunk of the pie. His pass-catching skills will also make him a valuable safety valve for Matt Cassel.
35 rush yardsJamaal Charles figures to get more carries, but Jones will likely get an opportunity or two to vulture a touchdown. His between-the-tackles style will make it more difficult for him to overcome the Chiefs' expected shakiness on the offensive line.
4 rec, 45 yards, 1 TDBowe has scored in each of his last two games against San Diego and will again be a popular red-zone target on Monday night. He's Matt Cassel's top receiving option and a worthy No. 2 fantasy receiver.
3 rec, 40 yardsChambers had seven catches for 70 yards and a score against the Chargers last season, but Dwayne Bowe did not play in that game, so Chambers won't be the top target this time around.
2 rec, 30 yardsThe Chiefs deployed their jack-of-all-trades at a multitude of positions in the preseason, and he'll likely see time at both running back and receiver on Monday night. His versatility makes him an intriguing sleeper, but be ready for some inconsistency.
2 rec, 20 yardsIn two games against San Diego last season, Kansas City's tight ends caught a grand total of one pass. Moeaki boasts a nice blend of pass-catching skills, but he won't make his mark in Week 1.
1 PAT, 1 FGSuccop managed just three extra points and one field goal in two games against the Chargers last year, due mostly to the futility of Kansas City's offense. The team should be charged up for its Arrowhead opener, but Succop is not a great starting option.
2 sacks, 1 INT, 0 Fumbles, 0 TDThe defense should be improved this season, but you'd be crazy to start KC against a Chargers team that rattled off 80 points in two meetings last year. Even without Vincent Jackson, San Diego will have no trouble moving the ball.