| Rank | Team | Player | Projection | Opponent | |
| 1 | ![]() | Peyton Manning | 310 pass yards, 3 pass TD, 1 INT Manning threw for 433 yards and three touchdowns in Week 1. Fantasy options don't come any more consistent than Manning, but don't expect 400 yards again. | vs | ![]() |
| 2 | ![]() | Philip Rivers | 280 pass yards, 3 pass TD The Chargers like to throw the ball and the Jaguars aren't very good at stopping it, so Rivers should have a big performance in Week 2. Expect him to throw multiple touchdown passes. | vs | ![]() |
| 3 | ![]() | Drew Brees | 285 pass yards, 2 pass TD Brees is a safe starter no matter the matchup. If the game remains close he'll throw early and often. | at | ![]() |
| 4 | ![]() | Tony Romo | 260 pass yards, 3 pass TD, 5 rush yards, 2 INT Romo threw 47 passes in Week 1, so the Cowboys certainly don't appear afraid to throw the ball. Romo should be able to find the end zone a couple times after throwing just one TD pass in the opener. | vs | ![]() |
| 5 | ![]() | Jay Cutler | 290 pass yards, 1 pass TD, 5 rush yards, 2 INT Mike Martz may have been just what Cutler needed -- Cutler completed 65 percent of his passes for 372 yards and two touchdowns in the opener. The Cowboys did a good job against Donovan McNabb in Week 1, but expect the Bears to continue throwing the ball a lot. | at | ![]() |
| 6 | ![]() | Aaron Rodgers | 240 pass yards, 2 pass TD, 15 rush yards, 0 INT The Bills only allowed 14 touchdown passes all of last season, so Rodgers may not put up the usual monster numbers. Still, the Packers' defense should be able to create some short fields for him. | vs | ![]() |
| 7 | ![]() | Michael Vick | 215 pass yards, 60 rush yards Vick shined in the opener and it looks as though Kevin Kolb is out for Week 2. Vick has instant fantasy value with the Lions on the docket. | at | ![]() |
| 8 | ![]() | Brett Favre | 240 pass yards, 2 pass TD, 1 INT Favre was a bit rusty in Week 1, but he should be able to rebound nicely against a Miami pass defense that was in the league's bottom 10 a year ago. | vs | ![]() |
| 9 | ![]() | Eli Manning | 240 pass yards, 2 pass TD, 1 INT The younger Manning threw three touchdown passes in Week 1, but he also threw three interceptions as well. Manning should be fired up for the big matchup with the Colts, and this game should be fairly high-scoring, so expect another strong fantasy perform | at | ![]() |
| 10 | ![]() | Kyle Orton | 255 pass yards, 1 pass TD, 5 rush yards, 1 INT Against one of the league's most porous secondaries from last season, Orton is assured at least decent numbers. He's safe to roll with if he's your best option. | vs | ![]() |
| 11 | ![]() | Matt Schaub | 255 pass yards, 1 pass TD, 1 INT Schaub faces a tough defense, but he's still among the top tier of fantasy quarterbacks and should get his numbers. | at | ![]() |
| 12 | ![]() | Matt Cassel | 240 pass yards, 1 pass TD, 10 rush yards, 1 INT Cassel struggled in preseason and still has yet to look like the QB he was in New England. Still, this matchup should be one of his cushiest of the season. | at | ![]() |
| 13 | ![]() | Derek Anderson | 235 pass yards, 2 pass TD, 2 INT Anderson is perhaps the biggest question mark the Cardinals have on offense. He has the weapons and the arm, but his accuracy is wanting. The Falcons should be a juicy matchup, in theory. | at | ![]() |
| 14 | ![]() | Matt Ryan | 205 pass yards, 2 pass TD, 1 INT The Cardinals have a good secondary, but Roddy White and Tony Gonzalez are mismatches most weeks and Ryan should take advantage. | vs | ![]() |
| 15 | ![]() | Tom Brady | 195 pass yards, 2 pass TD, 1 INT After a big three-touchdown performance in Week 1, Brady will be tested by the Jets in Week 2. Though Darrelle Revis may take Randy Moss out of the game, Brady proved in Week 1 that he can use other options as five receivers recorded over 40 yards. | at | ![]() |
| 16 | ![]() | Matt Hasselbeck | 200 pass yards, 1 pass TD, 5 rush yards He'll face a tough Broncos secondary, but the pass rush isn't too scary even for the Seahawks' offensive line. You can start him if you need to. | at | ![]() |
| 17 | ![]() | David Garrard | 205 pass yards, 1 pass TD, 15 rush yards, 2 INT Garrard tossed three touchdown passes in Week 1, but he threw for just 170 yards on 21 attempts in the game. Garrard's attempts will go up in Week 2 against the Chargers, but the touchdowns will go down. | at | ![]() |
| 18 | ![]() | Joe Flacco | 200 pass yards, 1 pass TD, 5 rush yards, 1 INT Flacco's two lowest yardage outputs last season came against the Bengals. He's healthier, more seasoned and has better weapons at his disposal, but you may have a QB with a better matchup on your bench. | at | ![]() |
| 19 | ![]() | Alex Smith | 210 pass yards, 1 pass TD, 2 INT Smith has emerged as competent quarterback and a borderline fantasy starter with the right matchup. Against the Saints and their ball-hawking secondary, it'd be wise to look elsewhere for a starting QB, however. | vs | ![]() |
| 20 | ![]() | Chad Henne | 200 pass yards, 1 pass TD, 2 INT Henne was held under 200 yards in the opener and did not find the end zone. He could be counted on more in Week 2 given the Vikings' ability to stop the run, but that could also lead to more mistakes. This is not a favorable matchup. | at | ![]() |
| 21 | ![]() | Donovan McNabb | 200 pass yards, 1 pass TD, 2 INT McNabb faces a so-so secondary, and could put up decent numbers assuming he gets some help from the rest of his offense. | vs | ![]() |
| 22 | ![]() | Josh Freeman | 165 pass yards, 1 pass TD, 30 rush yards, 2 INT Freeman played well in the opener after missing the last three weeks of the preseason with a broken thumb. Carolina struggled against the pass in the opener, but they were among the top five teams in the league last season in pass defense. | at | ![]() |
| 23 | ![]() | Dennis Dixon | 175 pass yards, 1 pass TD, 5 rush yards, 1 INT The Titans gave up a ton of passing yards last season, but also hawked the ball with 20 interceptions. Dixon is still a third-stringer starting out of necessity, so don't expect much. | at | ![]() |
| 24 | ![]() | Shaun Hill | 185 pass yards, 1 pass TD, 2 INT It's been three seasons since Shaun Hill showed the type of promise that once made him the Niners' starter, as the Lions are likely to find out against the Eagles. | vs | ![]() |
| 25 | ![]() | Vince Young | 165 pass yards, 1 pass TD, 20 rush yards, 2 INT Young has the reins, but he has yet to prove he can be a consistent passer. His breakout performance won't come against the Steelers. | vs | ![]() |
| 26 | ![]() | Carson Palmer | 175 pass yards, 1 pass TD, 2 INT Palmer was serviceable against the Ravens last season, but hardly extraordinary. Roll with him if there is nothing better on your bench. | vs | ![]() |
| 27 | ![]() | Jason Campbell | 155 pass yards, 1 pass TD, 10 rush yards, 2 INT Campbell had a rough first week against a pass defense that is not very strong, so he is a risky option against any opponent at this point. He should only be considered in two-QB leagues this week. | vs | ![]() |
| 28 | ![]() | Matt Moore | 165 pass yards, 1 pass TD, 2 INT Moore suffered a concussion in Week 1 and is questionable for this week's game. He will hand the ball off a lot even if he does play, so plan on going a different direction even in two-QB leagues. | vs | ![]() |
| 29 | ![]() | Mark Sanchez | 145 pass yards, 1 pass TD, 10 rush yards, 1 INT In two games against the Patriots last season, Sanchez averaged 150 yards, one touchdown, and two interceptions. Those numbers make him nothing more than a second quarterback in two-QB leagues for Week 2. | vs | ![]() |
| 30 | ![]() | Sam Bradford | 155 pass yards, 5 rush yards, 2 INT The Rams did not wait to get Bradford involved in the offense. Bradford attempted 55 passes in Week 1 and finished with 253 passing yards and a touchdown. However, the high number of opportunities also resulted in three interceptions. Don't expect a repeat. | at | ![]() |
| 31 | ![]() | Jake Delhomme | 135 pass yards, 1 pass TD, 5 rush yards, 2 INT As usual, there are much better fantasy QB options to choose from. If you have to start him, however, this is the week to do it. | vs | ![]() |
| 32 | ![]() | Trent Edwards | 110 pass yards, 1 pass TD, 5 rush yards, 3 INT Edwards completed just over 50 percent of his passes and threw for fewer than 150 yards in the opener. The Packers will be in his face a lot, so expect a couple of turnovers as well in Week 2. | at | ![]() |
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