| Pos. | Player | Projection |
| QB | Philip Rivers | 240 pass yards, 2 pass TD Vincent Jackson's absence has not hurt Rivers' production at all. Rivers has five touchdowns through two weeks -- expect a couple more this week against Seattle. |
| RB | Ryan Mathews | 1 rec, 10 rec yards, 40 rush yards, 1 rush TD Mathews is expected to play this week despite suffering an ankle injury in Week 2. The Seahawks have only given up 114 rushing yards in two games this season, so don't look for a huge game from a dinged up Mathews. |
| RB | Mike Tolbert | 1 rec, 5 rec yards, 5 rush yards Tolbert had a big performance in Week 2, but he won't give a repeat performance with Ryan Mathews expected to play in Week 3. |
| WR | Malcom Floyd | 5 rec, 75 yards, 1 TD Floyd showed what he is capable with a strong showing in Week 2, but he will find the going a bit tougher this week against Seattle corner Marcus Trufant. Still, Floyd should be started in most formats. |
| WR | Legedu Naanee | 4 rec, 40 yards Naanee caught just one pass last week after a big Week 1 performance, but he remains a nice sleeper option given the Chargers' ability to move the ball through the air. |
| WR | Patrick Crayton | 2 rec, 20 yards Crayton has yet to make much of an impact with the Chargers, so use other options this week. |
| TE | Antonio Gates | 8 rec, 90 yards, 1 TD Gates is off to a fast start with three touchdowns in two games. Expect his strong production to continue this week. |
| K | Nate Kaeding | 3 PATs, 2 FGs The Chargers routinely give Kaeding plenty of chances to score, and this week will be no different. Expect him to reach double digits. |
| Defense | 3 sacks, 2 INT This is a strong play at home this week against a Seattle team that lacks proven receivers. The Chargers forced six turnovers in Week 2 and should be good for at least a couple this week as well. | |
| Pos. | Player | Projection |
| QB | Matt Hasselbeck | 180 pass yards, 2 pass TD, 2 INT Hasselbeck's running touchdowns have really boosted his fantasy numbers, but he is not going to get those every week.The Chargers intercepted four passes last week, so be wary of using Hasselbeck this week. |
| RB | Justin Forsett | 2 rec, 15 rec yards, 40 rush yards Forsett has not done much as part of the Seahawks' RB carousel, but his 5.5 YPC average may help earn him a bigger share of the load going forward. Still, it's tough to start him until he secures the bulk of the carries. |
| RB | Julius Jones | 1 rec, 5 rec yards, 20 rush yards Jones is receiving a few carries a week, but he is not doing anywhere near enough to warrant a start this week. |
| RB | Leon Washington | 2 rec, 15 rec yards, 25 rush yards Washintgon is playing a bit role in the Seattle backfield, so don't count on him for much fantasy production. |
| WR | Mike Williams | 3 rec, 40 yards, 1 TD Williams continues to rehab his image while making Lions fans grind their teeth with every catch he makes. |
| WR | Deion Branch | 3 rec, 35 yards Branch offers little but a saftey valve for Haselbeck and even less for fantasy owners. |
| TE | John Carlson | 4 rec, 40 yards, 1 TD Through two games, Carlson has been the Seahawks' top target, gathering eight catches. He likely will be that again while also breaking in for a score. |
| K | Olindo Mare | 2 PATs, 1 FG Scoring chances have been few for Mare thus far, a situation that won't improve against the Chargers. |
| Defense | 1 sack, 1 Fumble The Seahawks have played reliably, if not spectacularly through two weeks. San Diego poses a tough test. | |