| Pos. | Player | Projection |
| QB | Ryan Fitzpatrick | 160 pass yards, 2 pass TD, 1 INT The Bills' passing game kicked into high gear last week, taking the Ravens into overtime in a three-point loss. Whether Fitzpatrick can stay hot remains to be seen, but this week's matchup against the Chiefs' 25th-ranked pass defense is a good one. |
| RB | Fred Jackson | 3 rec, 30 rec yards, 60 rush yards Jackson received 23 carries last week to seven for C.J. Spiller, so there should be no confusion as to who the workhorse in Buffalo is. If the passing game continues to click, bigger holes should open up. |
| WR | Lee Evans | 3 rec, 40 yards, 1 TD From a fantasy perspective, Evans' performance last week was better than all of his previous five games combined. While it would be foolish to expect that kind of production every week, he is a much better fantasy option with Ryan Fitzpatrick at QB. |
| WR | Steve Johnson | 3 rec, 50 yards, 1 TD Johnson's 158-yard performance is somewhat of an outlier this season (his previous high was 66 yards) but don't discount what Johnson has done so far. He now has touchdowns in four straight games, and could be a solid WR2/3 going forward. |
| WR | Roscoe Parrish | 3 rec, 30 yards With Ryan Fitzpatrick completing 29 passes for 374 yards last week, there were a lot of big days in the receiving corps. Parrish's eight receptions should definitely be considered a ceiling, but he's an option in deeper PPR leagues. |
| TE | Shawn Nelson | 1 rec, 5 yards Nelson had just two catches in his first game back from suspension and injury, and had a costly fumble in overtime. The Bills are bringing him back slowly on offense, so wait before even considering a pickup. |
| K | Rian Lindell | 2 PATs, 2 FGs Lindell has just 10 field-goal attempts this season, but if the Bills offense keeps its full head of steam, his opportunities should increase over the second half of the season. |
| Defense | 1 sack The Bills looked better on offense last week, but the defense was the same old story. They are a lousy play this week against a Chiefs team that can run at will. | |
| Pos. | Player | Projection |
| QB | Matt Cassel | 150 pass yards, 1 pass TD Cassel has been heating up lately, but the Chiefs are still a run-first team. Against a Bills team with a robust secondary, he should be riding your bench. |
| RB | Thomas Jones | 80 rush yards, 1 rush TD Both Jones and Jamaal Charles are just outside the top 10 for total rushing yards (13th and 11th respectively) and can be viable fantasy options, especially when the matchup is right. They go up against the league's worst run defense this week. |
| RB | Jamaal Charles | 2 rec, 15 rec yards, 80 rush yards, 1 rush TD The word "timeshare" drives fantasy players insane, but so far it has worked out pretty well in Kansas City. Both Charles and Thomas Jones have stayed productive on a weekly basis, despite the split carries, and are solid plays against Buffalo. |
| WR | Dwayne Bowe | 4 rec, 80 yards Bowe has 189 yards receiving in his past two games, 37 yards more than his previous four combined. Be wary of buying him too high at this point in the season, but he has definitely earned starting consideration against a bad Bills defense. |
| WR | Dexter McCluster | 2 rec, 20 yards McCluster had nine touches last week (four carries, five catches) in what could be considered a sign of the coaches' growing confidence in him. There isn't much value at the moment, but he may be worth stashing on your roster if you have room. |
| TE | Tony Moeaki | 3 rec, 35 yards, 1 TD The Bills are giving up nearly 70 yards and more than one touchdown a game receiving to tight ends this season. Moeaki is worth considering even over some of the more elite tight end options this week. |
| K | Ryan Succop | 3 PATs, 1 FG Succop had zero field-goal attempts last week thanks to the running game's efficiency in the red zone. A solid running game has led to few field goal attempts for Succop, with just 10 on the season so far. |
| Defense | 3 sacks, 1 INT Ryan Fitzpatrick torched the Ravens for 374 yards last week. They weren't all garbage yards either -- the Bills lost by three points in OT. The Chiefs are a bad play this week, coming in with the league's 25th-ranked pass defense. | |