| Rank | Team | Player | Projection | Opponent | |
| 1 | ![]() | ![]() |
Tom Brady345 pass yards, 3 pass TDs
Brady is on pace to throw for 4,800-plus yards for the third time in his career, with at least 32 touchdown passes for the fourth time. He has thrown for at least 335 yards and three touchdowns in his past three games against the Bills. | vs | ![]() |
| 2 | ![]() | ![]() |
Matt Ryan305 pass yards, 3 pass TDs, INT, 14 rush yards
While the Cowboys held Ryan without a touchdown pass, he was still able to throw for 342 yards, marking the third time this season he eclipsed 300 yards. Ryan remains a must-start player, especially against a Saints defense that's among the worst in the NFL. | at | ![]() |
| 3 | ![]() | ![]() |
Peyton Manning310 pass yards, 3 pass TDs, INT
For the fifth consecutive game, Manning threw for three touchdowns. He's a top-five fantasy quarterback after nine weeks, and he should keep it going against a Panthers team that has just six interceptions. | at | ![]() |
| 4 | ![]() | ![]() |
Matthew Stafford297 pass yards, 3 pass TDs, INT
Last season Stafford completed close to 70 percent of his attempts in two games against Minnesota, with four touchdowns and no interceptions. Earlier this year against Minnesota Stafford attempted 51 passes and threw for 319 yards. More, please. | at | ![]() |
| 5 | ![]() | ![]() |
Eli Manning302 pass yards, 2 pass TDs
Frustrated with Manning? You'd be crazy to give up on him now. He has faced very good defenses in recent weeks, so don't bail before he makes amends, starting this week against a Bengals defense allowing opposing passers a 99.0 QB Rating. | at | ![]() |
| 6 | ![]() | ![]() |
Joe Flacco283 pass yards, 2 pass TDs
All the talk about Flacco taking a step this season ... well, it was just talk. He's been the same play-it-safe game manager he's always been. This week, however, fantasy owners could see a different Joe. A date with the Raiders invites a high-scoring, back-and-forth affair. | vs | ![]() |
| 7 | ![]() | ![]() |
Tony Romo297 pass yards, 2 pass TDs, INT, 14 rush yards
Romo, strained back and all, has one last chance to keep playoff hopes alive for Dallas. He faces an Eagles secondary that was once listed among the league's best, but lately has been exploited by Drew Brees and Matt Ryan. | at | ![]() |
| 8 | ![]() | ![]() |
Josh Freeman265 pass yards, 2 pass TDs, INT, 14 rush yards
Freeman threw for 247 yards and two touchdowns at Oakland in Week 9, and he now has 11 touchdown passes in his past four games. The Chargers are better against the run than the pass, so consider Freeman a low-end fantasy starter in Week 10. He's on pace for a 4,000-yard season. | vs | ![]() |
| 9 | ![]() | ![]() |
Andrew Luck287 pass yards, 2 pass TDs, INT
Luck is one of four NFL quarterbacks averaging more than 300 passing yards per game. The others: Drew Brees, Tom Brady and Peyton Manning. Luck has indeed arrived. | at | ![]() |
| 10 | ![]() | ![]() |
Cam Newton185 pass yards, pass TD, 2 INTs, 40 rush yards, rush TD
Newton threw and rushed for a touchdown at Washington in Week 9, although a much bigger game was expected of him against a bad Redskins defense. It was good to see Newton play well once again, but that could change against Denver. | vs | ![]() |
| 11 | ![]() | ![]() |
Andy Dalton264 pass yards, 2 pass TDs, INT
Yes, he throws a lot of interceptions (at least one in every contest so far this season), but so what? Dalton should reach 4,000 yards and 25-plus touchdown passes. He'll face a secondary this week ranked 26th in passing yards allowed. Sounds like a winning matchup to us. | vs | ![]() |
| 12 | ![]() | ![]() |
Drew Brees260 pass yards, 2 pass TDs, INT
Brees threw for two touchdowns against the Eagles in Week 9 and now has 12 touchdowns in his past four games. In two games against Atlanta last season, Brees threw six touchdown passes and just two interceptions. | vs | ![]() |
| 13 | ![]() | ![]() |
Alex Smith205 pass yards, 2 pass TDs
Over his previous three games before the Week 9 bye, Alex Smith threw for an average of 191 yards with four total passing touchdowns. He only threw for three touchdowns in two games against the Rams last year, so consider another fantasy quarterback in Week 10. | vs | ![]() |
| 14 | ![]() | ![]() |
Philip Rivers215 pass yards, 2 pass TDs, INT, 12 rush yards
Rivers took advantage of a weak Chiefs secondary to post 220 yards, two touchdowns and an interception in Week 9. The Buccaneers aren't much better in the defensive backfield, making Rivers a borderline fantasy starter once again. | at | ![]() |
| 15 | ![]() | ![]() |
Michael Vick229 pass yards, pass TD, INT, 38 rush yards
It appears Vick will remain the Eagles' starting quarterback for the rest of the season, regardless of how ugly things get. He toyed with Dallas twice last year, but that feels like ancient history now. Fantasy owners should consider keeping him out of the lineup. | vs | ![]() |
| 16 | ![]() | ![]() |
Ben Roethlisberger217 pass yards, 2 pass TDs, INT
Roethlisberger is on pace to deliver one of his best seasons, but this is not a good matchup. Teams simply do not need to throw on the Chiefs; opponents have attempted just 210 passes against Kansas City this year, by far the fewest in pro football. Roethlisberger will stand down and let the running game do the talking. | vs | ![]() |
| 17 | ![]() | ![]() |
Ryan Tannehill260 pass yards, pass TD, INT, 18 rush yards
Tannehill threw for 290 yards, his second-most passing yards of the season, against the Colts in Week 9. The rookie hasn't thrown an interception since Week 4, although he has just three touchdown passes since that week, too. He's a decent QB2 for Week 10 against the Titans. | vs | ![]() |
| 18 | ![]() | ![]() |
Christian Ponder215 pass yards, pass TD, INT, 17 rush yards
Ponder's completion percentage has been below 60.0 in each of his past three games, and now he'll face a hungry Lions front four. It could be a long afternoon for Minnesota's second-year quarterback. | vs | ![]() |
| 19 | ![]() | ![]() |
Carson Palmer249 pass yards, pass TD, INT
Palmer has already matched his touchdown total from 2011, but has half as many interceptions. He is on pace to set career highs for completions and yards. If there is a reason for concern this week, it's that the Ravens have allowed just six passing touchdowns, tied for fewest in the league. | at | ![]() |
| 20 | ![]() | ![]() |
Russell Wilson190 pass yards, pass TD, INT, 20 rush yards
Wilson has thrown five touchdown passes and one interception in his past two games, and now the rookie faces a Jets team that ranks in the top 10 against the pass. He's playing well, but there are better options. | vs | ![]() |
| 21 | ![]() | ![]() |
Jay Cutler228 pass yards, pass TD, INT
It's not a matter of if Cutler will get knocked down this week, but rather how he will respond. The Texans allow opposing passers a 75.4 QB Rating and will do all they can to get into the head of Chicago's easily agitated quarterback. | vs | ![]() |
| 22 | ![]() | ![]() |
Matt Schaub219 pass yards, pass TD, INT
All Schaub has to do is travel to unfriendly Soldier Field to face a Bears defense that leads the league in interceptions (17) and ranks third in sacks (25). No sweat, right? | at | ![]() |
| 23 | ![]() | ![]() |
Blaine Gabbert206 pass yards, pass TD, INT
Don't let the Colts' poor pass defense fool you: Gabbert guided Jacksonville to its only victory earlier this year against the Colts, but he completed less than 50 percent of his passes for 155 yards. No matter how quickly his non-throwing shoulder heals, don't get suckered into picking up Gabbert. | vs | ![]() |
| 24 | ![]() | ![]() |
Sam Bradford205 pass yards, pass TD, 2 INTs, 14 rush yards
While Bradford didn't play in either game against the 49ers last year, he did throw for 250 yards and one touchdown in each game against them in 2010. Even so, Bradford isn't a good fantasy option in Week 10, with San Francisco's defense having an extra week to prepare. | at | ![]() |
| 25 | ![]() | ![]() |
Mark Sanchez185 pass yards, pass TD, 2 INTs, 17 rush yards
The Jets have been forced to pass in their past couple games, but Sanchez is still not a recommended fantasy starter. The Seahawks are tough against the pass and the run, and despite having two weeks to prepare for this game, Sanchez should have a troublesome Week 10. | at | ![]() |
| 26 | ![]() | ![]() |
Ryan Fitzpatrick185 pass yards, pass TD, 2 INTs, 14 rush yards
For the third time in four games, Fitzpatrick failed to throw a touchdown pass. The Patriots aren't good against the pass, and Fitzpatrick threw four touchdowns against them in Week 4, but he also threw four interceptions. Start him at your own risk. | at | ![]() |
| 27 | ![]() | ![]() |
Matt Hasselbeck205 pass yards, pass TD, 2 INTs
Hasselbeck completed 20 passes for 194 yards in Week 9 against Chicago, and he threw just one touchdown pass for the fifth game in a row. With Jake Locker (shoulder) still sidelined, Hasselbeck will be under center again in Miami, but fantasy owners should steer clear. | at | ![]() |
| 28 | ![]() | ![]() |
Matt Cassel189 pass yards, INT
Depending on Brady Quinn's recovery time, Cassel may not even see the field Monday. Cassel has done nothing this season to save his job, and this week the Chiefs face the league's top pass defense. | at | ![]() |