We've seen this script before. Jacksonville has terrible offense. MJD doesn't show up in a game or two early. MJD figures it out and has a great year. Don't worry about him.
Ben Tate was a more efficient runner last week, but Foster still had 24 touches, including six catches on eight targets. He'll be the bellcow as long as he's healthy, but coach Gary Kubiak has said he wants a more equal distribution this week.
The Jets shut down Martin, allowing just 65 yards on 24 carries. I fully expect him to bounce back this week against a softer New Orleans defense that surrendered 77 yards to Steven Jackson on 11 carries, though most of that was on one run.
McCoy absolutely eviscerated the Redskins, running for 184 yards and a touchdown. If he holds up, he could be the No. 1 player in fantasy.
Charles was on his way to a big day before leaving with a quad injury. He finished with exactly 100 yards from scrimmage and a touchdown, but the best news came after the game when his quad injury was deemed minor.
As I said all summer, Bush and the Lions are a match made in heaven. It all started last week with 191 yards from scrimmage and a touchdown. He'll easily have the best year of his career.
The Dolphins shut Richardson down last week, as he ran for just 47 yards on 13 carries. He'll show up this week, keeping the Browns in the game before the Ravens put them away.
Rice ran for just 36 yards on 12 carries, but he found the end zone and caught eight passes for 35 yards. He'll keep on getting 20-plus touches per game, giving him an awfully high floor.
Well that couldn't have gone any worse. Still, the Giants have to rely on Wilson, who will redeem himself against the Broncos. If his owner in your league is getting jumpy, try to take advantage.
Williams had a nice showing against a strong defense, running for 76 yards on 16 carries (4.8 YPC) and catching three passes for 14 yards. He'll take advantage of a much weaker defense in Buffalo.
Jackson got just 11 carries, but he racked up 77 yards and also caught five passes for 45 yards in the opener. He'll be fired up to play his former teammates this week, and they know what he's capable of producing.
Forte totaled 91 yards from scrimmage and punched in a 1-yard touchdown run against the Bengals. He'll find a lot more room to operate this week.
Peterson's boom-or-bust nature showed up again last week. He ran for a 78-yard touchdown on Minnesota's first play from scrimmage, but finished with just 93 yards on 18 carries. Of course, he scored two more times. The Bears present as tough a matchup as he'll see all year.
Murray quietly racked up 125 yards from scrimmage against the Giants last Sunday night, running for 4.3 yards per carry. He'll score his first touchdown of the season on Sunday.
Spiller ran for just 41 yards on 17 carries, and his five receptions went for just 14 yards. It was troubling for his owners to see Fred Jackson rack up 107 total yards, but Spiller will give them a useful day this week.
Ridley found himself stuck on the bench after fumbling in the second quarter, but with Shane Vereen out until at least Week 11 with a broken wrist, Bill Belichick will have to go right back to him this week.
Johnson had just 70 yards on 25 carries, and wasn't targeted once in the passing game. The worry here is that Jake Locker could undermine the entire offense.
Well that wasn't quite the 2013 debut Miller and his fantasy owners hoped for. Luckily, Daniel Thomas isn't a real threat to become a workhorse. Miller will bounce back this week.
Bernard got just four carries in his NFL debut. Though his ceiling remains high, you can't start him until we see him take on a larger role in the offense.
Sproles kicked off 2013 in a big way, catching six passes for 88 yards. He's a boom-or-bust guy who will go boom again this week.
Mathews looked sluggish against the Texans, running for just 33 yards on 13 carries. He did have a 14-yard touchdown reception and is worthy of a flex start this week.
Morris had a dreadful night, fumbling on his first carry of the season and dropping a pitch that resulted in a safety. He saved his night with a touchdown, and should have a better showing against the Packers.
Lynch had a brutal day against the underrated Carolina defense, running for 43 yards on 17 carries. It doesn't get any easier this week.
Tate looked good on Monday night, running for 55 yards on nine carries, but it'll be hard to trust him as a starter with a healthy Arian Foster.
Bradshaw's value got a huge spike with Friday's news that Vick Ballard is done for the season. Like the Colts, owners should consider riding Bradshaw at RB2 or flex as long as he'll hold up.
The Cardinals have a good defense, but Richardson's performance left me feeling underwhelmed. I expect more of the same this week.
As the goal-line back, Bell will cash in on the hard work done by Reggie Bush and the rest of the Lions' offense, just like he did twice last week. It doesn't make him a fantasy starter, but he's worth rostering if you can.
McFadden had just 48 yards on 17 carries and caught three passes for 18 yards. He remains a flex option, but the lack of burst from last year appears to have carried over to 2013.
Powell is definitely the Jets back you want if you have to own one, but he won't factor into fantasy leagues until we get to the bye-week portion of the schedule.
The bad news: Mendenhall ran for just 60 yards against the Rams. The good news: He got 16 carries and will continue to be the primary ball carrier.
Green-Ellis needs volume and short-yardage touchdowns to be effective. He got the score last week. He won't get one this week.
After struggling against the Packers, Gore won't find it any easier in Seattle. He'll fail to get to 50 yards for the second straight week.
Lacy predictably struggled in a tough matchup last week, but his owners will start to get nervous when he struggles again in a much more favorable draw Week 2.
C.J. Spiller was a first-round pick, but Jackson had the better Week 1, racking up 107 total yards. He may be able to carve out a decent fantasy role.
Moreno got the starting nod last week, and it will likely remain that way until the Broncos trust Montee Ball in pass protection. Still, he isn't worth starting.
Thomas is probably the best pure running back on the Saints. Of course, that means nothing.
Ball was in the game late, but until he starts seeing regular time, he cannot be relied on in fantasy leagues.
Woodhead is not a viable fantasy option so long as Ryan Mathews and Ronnie Brown are in town.
Given a chance to take the reins, Redman ran for nine yards on eight carries and fumbled twice. With center Marukice Pouncey out for the year, this is a situation you want to avoid until Le'Veon Bell returns.
Brown becomes Bradshaw's backup with Ballard out and we wouldn't be surprised if the Colts have to turn to him as the starter this season. He's a bonafide pick-up-and-stash candidate.
Brown looked explosive in limited duty, and could be a flex play from week to week. This is not one of those weeks, though.
Rodgers had just two carries and one target last week. This is what happens when the Falcons have a workhorse running back.
The Giants signed Jacobs on Tuesday as insurance, but you shouldn't be considering him in fantasy leagues.
Ivory touched the ball 10 times last week, but ran for just 15 yards. He should remain glued to your bench.
Another year, another non-existent run game for the Saints. And it won't matter in real life. Stay away from Ingram.
Thomas may have picked up a one-yard touchdown run, but Lamar Miller is still the man in Miami. Thomas is worth rostering thanks to Miller's terrible Week 1 performance, though.
Hillman looks like he'll have his change-of-pace role all year, but that won't make him relevant in fantasy leagues.
DeAngelo Williams dominated the work out of the backfield, and ended up with a very impressive showing against the Seahawks. Tolbert's nothing but a depth guy.
So long as Ray Rice is healthy, Pierce will not be worth considering in fantasy leagues.
Hunter simply doesn't get enough touches to make a fantasy impact. He's worth owning in case Frank Gore gets hurt.
Davis carried the ball just four times for 12 yards. Short of a Jamaal Charles injury, he's nothing more than a handcuff.
Battle picked up 21 yards and a touchdown on eight carries, but isn't of any consequence in fantasy leagues.
Greene ran for 18 yards on four carries against the Steelers. Until further notice, he won't be getting enough touches to make a fantasy impact.
SI Now: Adrian Peterson thinks Johnny Football is NFL Ready
SI Now: Adrian Peterson on the Vikings' future at quarterback