Manuel appears to be getting it very early in his NFL career. He threw for 296 yards and 7.6 yards per attempt last week, and is a real factor in two-QB leagues.
Spiller ran for 103 yards on 16 carries and caught four passes for 26 yards last week. Even against a Jets defense that has shut down Doug Martin and Stevan Ridley, I think Spiller will have a day.
Jackson totaled 53 yards from scrimmage and a touchdown last week, and looks like a flex play even though he's second fiddle to C.J. Spiller.
Johnson had a huge day, posting eight receptions for 111 yards and the game-winning TD. I think he's a WR2 for the rest of the year.
Woods could be worth a speculative add. He had four catches on six tagers for 68 yards last week.
One taget Week 1, three targets Week 2. Stay away.
Chandler caught three passes for just 10 yards, and doesn't look like much of a fantasy option.
Carpenter went 3-for-4 on field goals last week, including one from 55 yards. In what should be a defensive struggle, I like him to have a big fantasy day.
The Bills played a great game defensively last week, sacking Cam Newton six times, intercepting him once and limiting him to 6.0 yards per attempt. They're a great stream option this week.
Smith struggled against the Patriots, throwing three interceptions and looking confused for most of the game. He's not a fantasy option no matter your format.
Powell had 70 yards and a touchdown on 15 touches against the Patriots. He's a fringe flex option.
Ivory racked up 52 yards on 12 carries and would be a decent flex player if Bilal Powell got hurt.
Kerley's expected back after missing Week 2 with a concussion.
Hill definitely has some big-play ability, and he showed it in catching four passes for 86 yards last week.
Holmes had three receptions for 51 yards but there couldn't be a more lackluster receiver in the fantasy game.
Winslow had just three catches for 16 yards last week, proving that he isn't worth owning given all the reliable options at tight end in today's NFL.
Folk is 4-for-4 on field goals this year, and should produce a nice fantasy day going up against a solid Buffalo defense.
The Jets allowed just 13 points to the Patriots, but I'd attribute that to the Patriots shaky offense as much as to the Jets. You should be able to find a better option this week.