Newton didn't have his best game through the air last week, throwing for 249 yards, one touchdown and two picks, though he made up for it with a rushing score. The Niners present a very tough challenge.
Jonathan Stewart outgained DeAngelo Williams by one yard on four fewer carries last week. Williams' days of fantasy relevance could be numbered.
Stewart ran for 43 yards on nine carries in his 2013 debut. He shouldn't be trusted against San Francisco, but he could be the lead back in Carolina before it's all said and done.
Tolbert cashed in again in short-yardage last week. Even with Jonathan Stewart back, he'll retain goal-line duties.
Smith is a low-end WR3 this week against a stout San Francisco defense. The Panthers will have to go to the air though if they expect to win.
LaFell cannot be trusted in a matchup with the 49ers, who have allowed the seventh-least fantasy points per game to wide receivers.
Ginn had just one catch last week and should not be considered against the San Francisco defense.
Olsen had 66 yards and a touchdown last week. You're starting him if you own him, but the 49ers have allowed the fifth-fewest points per game to tight ends.
Gano made both of his field-goal attempts last week, including a 55-yarder. He is a perfect 12-for-12 on the year.
The Panthers forced the Falcons into four turnovers, but the 49ers are a different animal. Carolina is a strong option every week, but this is not a great matchup.
The Panthers allow the second-fewest fantasy points per game to quarterbacks. Look for the 49ers to try to dominate with the run game this week.
Carolina has been strong against the run this year, but San Francisco has been running at will on its current win streak. It should be a good test for Gore.
Boldin has just 343 yards in seven games since going for 208 in the season opener. Play him at your own risk.
If the Niners can keep Colin Kaepernick clean, Davis could have a big day. The Panthers have a great front seven, but a mediocre secondary.
The 49ers aren't lighting up the scoreboard this year, which makes Dawson a dicey fantasy play from week to week.
You start them every week, even in non-optimal matchups like this one.
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