Charles had a fantasy day for the ages last week, racking up 215 total yards and five touchdowns. He has as strong a case as Peyton Manning for the MVP award.
Murray could be a championship game star going up against a Washington defense that has allowed the third-most fantasy points to running backs this year.
Gore should be in for a huge day against an Atlanta defense that has allowed the seventh-most fantasy points to running backs this year.
Forte had 127 yards on 24 carries last week. He's an RB1 against Philadelphia, just like he is every week.
McCoy should have a monster game against a Chicago defense that has allowed the fourth-most fantasy points to running backs this year. I'm setting his total yards over/under at 167.5.
Mathews' excellent season continued last week, as he ran for 127 yards and a touchdown on 29 carries. The Raiders have allowed the sixth-most fantasy points to running backs this year.
Stacy trampled over the Saints for 133 yards and a score on 28 carries. He's an RB2 this week.
Bush totaled 101 yards from scrimmage and scored after missing one game with a calf injury. He's an RB1 this week.
Jones-Drew missed last week's game because of a hamstring injury. We'll update his status later in the week. If he cannot start, Jordan Todman will give it a go again.
No one can blame Morris for the nightmare season in Washington. He can cap off a great year for his fantasy owners against a Dallas defense that has allowed the most fantasy pints to running backs this year.
Moreno had just eight carries for 19 yards last week. He should have a better day with the Broncos likely to be protecting a lead most of the game.
Detroit has a fearsome front four, but you should still consider Brown an RB2 this week.
Lynch could be in for a long day Sunday, as the Cardinals have allowed the fewest fantasy points to running backs this year. Having said that, you're starting him with confidence.
Rainey could be a key player this week, as the Rams have allowed the fifth-most fantasy points to running backs this season.
Lacy carved up the Cowboys for 141 yards and a touchdown last week. The Steelers will present a much tougher challenge, making him an RB2.
The Patriots have been vulnerable to the run, making Rice a potentially crucial player in Week 16.
The Vikings have allowed the eighth-most fantasy points to running backs and second-most to quarterbacks, making a pass-catching back like Bernard a likely star this week.
Williams racked up 168 yards from scrimmage and a touchdown last week with Jonathan Stewart inactive. He'll be an RB2 should Stewart miss this week's game.
Miller had 61 yards on 15 carries last week. Unless those touches increase, he won't be better than an RB3.
Johnson continues to make his mark as a receiver, catching three passes for 51 yards and a touchdown last week. Consider him an RB2.
Peterson has declared himself good to go for Sunday's game. That's a sigh of relief for his owners and possible dread for said owners' opponents.
Green-Ellis can be considered a RB2 against a Minnesota defense that has allowed the eighth-most fantasy points to the position this year.
Vereen had just three catches for eight yards last week. The bet here is that he gets back on track this week.
Jackson picked up 80 yards on 17 carries last week. He's a low-end RB2 against the Dolphins.
Ivory had 66 yards on just 11 carries last week. He's an RB3 against the Browns.
Jennings returned to the lineup last week, running for 91 yards and two touchdowns on 23 carries. He's worth considering.
Johnson will start for Houston after the team placed Ben Tate on IR with a rib injury. I'm bearish on him this week. If and when Denver builds a big lead, the Texans will be forced to eschew the run.
Bell did his dual-threat thing again, racking up 107 total yards last week. He should have a good game against the Packers.
Mendenhall had 69 yards and two touchdowns last week. Consider him a RB3 against a Seattle defense that has allowed the third-fewst fantasy points to running backs this year.
Ellington had 158 yards from scrimmage last week and remains a RB3, though Seattle has allowed the third-fewest points to running backs this year.
Spiller got just 13 carries last week, but he managed to pick up 67 yards. He's not trustworthy enough for me.
The Panthers have allowed the second-fewest fantasy points to running backs this year, making Thomas no better than a low-end RB2 this week.
Woodhead is no Jamaal Charles, but you can bet he'll be featured this week after what Charles did to the Raiders a week ago.
The 49ers have allowed just 3.9 yards per carry this year, though they have surrendered 10 rushing touchdowns.
It has been a down year for Sproles, but he can be considered an RB3 against a Carolina defense that has had problems with pass-catching backs.
Ball got just three carries last week after being a mainstay in the Denver offense for nearly a month. It's hard to predict how he'll be used this week, but he should get more touches with Denver likely to be nursing a lead.
Ogbonnaya ceded most of the carries to Edwin Baker last week. Even if Willis McGahee is inactive once again, you can't consider Ogbonnaya.
Tolbert isn't a good option for fantasy owners in Week 16.
With Reggie Bush looking healthy, Bell should be on your bench this week.
Powell was once again second in the pecking order behind Chris Ivory last week. You should not be thinking about starting him.
Ridley still appears to have one foot in Bill Belichick's doghouse. He cannot be considered a fantasy starter this week.
McGahee was inactive last week, but expects to play on Sunday. We'll update his status later in the week.
Gerhart figures to be back int he Vikings' lineup as well. He'll only get a bunch of carries if Peterson leaves the game early again.
Blount led the Patriots in carries last week, but the Ravens have allowed the fifth-fewest fantasy points to running backs this year.
Richardson would start if Donald Brown has to sit out, but there's no way you could consider him a starter against Kansas City.
Thomas had just five carries a week ago and cannot possibly be trusted in Week 16.
Rodgers has zero fantasy value.
Pierce is not a fantasy option in Week 16.
Ingram shouldn't be anywhere near a fantasy starting lineup going against the Panthers.
Stewart was inactive last week and is likely facing the same fate this week.
Asiata ran for three touchdowns last week, but picked up just 51 yards on 30 carries. You should not be considering him for Week 16.
Brown left last week's game with a stinger and could sit this week. The Colts brought in former Chief Shaun Draughn.
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