HOUSTON (Ticker) -- Tulane returned Houston to its losing ways.
J.P. Losman passed for 208 yards and two touchdowns as Tulane defeated the mistake-prone Cougars, 34-13, in the Conference USA opener for both teams.
Houston (1-1, 0-1 C-USA), which snapped a 15-game losing streak last week with a 24-10 victory over Rice, opened a 10-7 lead on Anthony Evans' 14-yard run with 10:11 remaining in the third quarter.
But the Cougars could not overcome seven turnovers as Tulane (2-0, 1-0) took the lead for good less than two minutes later on Losman's 28-yard touchdown pass to Roydel William.
Houston appeared in position to regain the lead, but running back Joffrey Reynolds fumbled and defensive end Floyd Dorsey returned it 95 yards to make it 21-10 in the final minute of the period.
It was one of four fumbles for the Cougars, who coughed up the ball on its first two possessions of the fourth quarter. Tulane converted those turnovers into field goals of 24 and 44 yards by Seth Marler, stretching its lead to 27-10.
Mewelde Moore paced Tulane on the ground with 90 yards on 19 carries.
Barrick Nealy completed 19-of-38 passes for 181 yards for the Cougars but also threw three interceptions. Reynolds rushed for 143 yards on 29 carries.