GREENVILLE, North Carolina (Ticker) -- Art Brown ran for a career-high 185 yards and two touchdowns to lead East Carolina to its first victory of the season, a 24-20 Conference USA triumph over Tulane.
The Pirates (1-2, 1-0 C-USA) lost their first two games by a combined 12 points combined and entered their matchup against the Green Wave with a struggling passing game as wide receiver Richard Alston is suffering from mononucleosis.
But Brown picked up the slack with the best performance of his career.
Brown had 27 carries and gained 24 more yards than he recorded in his first two games combined. Marvin Townes rushed for 88 yards on 14 carries as East Carolina gained 226 of its 318 total yards on the ground.
Paul Troth completed only 8-of-18 passes for 92 yards. Alston, who was considered doubtful during the week, played despite the illness and caught three passes for 23 yards.
Tulane (2-1, 1-1) took a 20-17 lead on Seth Marler's 32-yard field goal with eight minutes left in the third quarter. But Brown had a four-yard scoring run just over seven minutes later to give East Carolina the lead for good.
It was the fourth rushing touchdown of the season for Brown, who had only two in his first two seasons.
Pirates kicker Kevin Miller had a field goal and three extra points, moving him into third place on the school's all-time scoring list with 216 points.
Tulane was handed its first loss of the season, despite totaling 343 yards.
J.P. Losman completed 31-of-48 passes for 236 yards and threw the game's only interception. His favorite target was Roydel William, who had a season-high 10 receptions for 87 yards.
Green Wave running back Mewelde Moore gained 114 yards on 30 carries and caught six passes for 34 yards.