STATE COLLEGE, Pennsylvania (Ticker) -- Brad Banks and Iowa erased all the positive karma surrounding Penn State.
Banks threw four touchdown passes, including a six-yarder to C.J. Jones in overtime, as the Hawkeyes squandered a 22-point lead in the fourth quarter before escaping with a 42-35 victory over the 12th-ranked Nittany Lions.
Fred Russell carried 35 times for 142 yards and one score for the Hawkeyes (4-1, 1-0 Big Ten), who defeated the Nittany Lions for the third straight season and for the second straight year in overtime. The game marked the conference opener for both teams.
Penn State (3-1, 1-0) has endured back-to-back losing seasons, but the program appeared to be back on course after opening the year with three straight wins, including a lopsided triumph over Nebraska.
"We stunk for a while. We were just flat," Penn State coach Joe Paterno said. "They did a couple of things and we were flat. Iowa is a good team."
The loss left the Nittany Lions bitter and frustrated.
"We all know that we are a better team than they are," Penn State linebacker Derek Wade said. "We should have won and we all know it. If we had played better in the first half then we would all be walking out of here smiling right now."
Iowa is off to its first 4-1 start since 1997, two years before current coach Kirk Ferentz took over.
"We got guys with high character," Ferentz said. "We're not the most talented team in the world, but I think we got guys that fight and work hard and that showed in the fourth quarter."
Iowa recorded its first road win over a ranked opponent since defeating Penn State in 1996.
The Nittany Lions dug themselves a deep hole before tying the game on an eight-yard TD pass from Zack Mills to Bryant Johnson with 80 seconds left, capping a 22-point quarter.
But Banks, a senior making his first Big Ten Conference start, kept his composure, finding Jones over the middle on the first possession of overtime. It was the second TD catch of the day for Jones, who caught seven passes for 46 yards.
"We had a confident mood on the sideline," Russell said of the overtime period. "We just kept pushing each other and hoping the defense would hold it down."
Penn State moved to the Iowa 5-yard line on its OT possession before Mills' fourth-down pass under pressure fell incomplete.
On second down, Tony Johnson caught a ball at 2, but was ruled out of bounds on a close play. Paterno was irate with the call, chasing after the officials as they left the field.
"I thought they made a couple of lousy calls on the other side of the field," Paterno said.
The officials caught plenty of heat from the Penn State sidelines. According to ESPN, former Nittany Lions linebacker LaVar Arrington, currently with the Washington Redskins, was asked to leave the field after repeatedly yelling at the officials.
Iowa overcame a huge game from Mills, who completed 23-of-44 passes for a school-record 399 yards and four scores.
"We came out flat and it showed," Mills said. "I said earlier in the week that Iowa was underrated. They came out and showed they are a great football team."
The Hawkeyes led 35-13 early in the fourth quarter and appeared to be on the verge of putting the game way out of reach when Jovon Johnson returned an interception 33 yards to the Penn State 1.
But Russell fumbled on the next play, giving the Nittany Lions life and starting their comeback.
Larry Johnson went up the middle for a 36-yard TD run, cutting the lead to 35-20.
Following a 12-yard punt by Iowa's David Bradley, the Nittany Lions capitalized on a 44-yard TD pass from Mills to Tony Johnson. Holder Chris Ganter ran in on the two-point conversion, cutting the lead to 35-28.
Penn State's defense held and Mills found Bryant Johnson in the back of the end zone for a game-tying TD pass.
Banks threw TD passes of four yards to Jones and 22 yards to Ed Hinkel Hinkel that gave the Hawkeyes a 23-0 lead with 6:04 left in the second quarter.
Nate Kaeding kicked two long field goals, including a 47-yarder that gave the Hawkeyes a 10-0 lead. Russell scored on a 20-yard TD run to increase the lead to 17 points after one quarter. Mills cut the lead to 23-7 on a 28-yard TD pass to Bryant Johnson with 1:25 left in the first half before Kaeding made it 26-7 at halftime when his career-long 55-yarder glanced favorably off the left upright.
Penn State tried to rally early in the third quarter when Larry Johnson scored on a one-yard run. But the momentum quickly swung back to the Hawkeyes when the extra point was blocked and D.J. Johnson returned the ball the length of the field for a two-point conversion.
Maurice Brown increased the lead to 35-13 when he caught a short pass, shook off defensive back Chris Harrell and raced up the sideline into the end zone for a 54-yard score with 8:03 left in the third quarter. Brown caught four passes for 100 yards.