TUCSON, Arizona (Ticker) -- Louisiana State may want to visit the Grand Canyon State more often.
Matt Mauck completed 9-of-10 passes, threw for a touchdown and ran for another as the 13th-ranked Tigers rolled to their most lopsided road win in 45 years, a 59-13 rout of Arizona.
LSU was visiting the state of Arizona for the first time and left with one of the most impressive wins in school history. It was its biggest road victory since a 62-0 triumph at Tulane in 1958.
"I'm really pleased with the way we came on the road and came into somebody else's house and dominated the game," LSU coach Nick Saban said.
Arizona was handed its worst loss since a 54-0 defeat against Washington in 1991. The Wildcats had not been beaten this badly at home since losing to Arizona State, 47-0, in 1958.
The loss did little to help the job security of Arizona coach John Mackovic, who went 4-8 last season and survived a player revolt.
"LSU is a very good football team," Mackovic said. "We shouldn't take that for granted. They came and played very well, capitalized on every field opportunity. They just thoroughly whipped us."
Joseph Addai ran for 86 yards and sparked the rout with a pair of touchdowns in the first quarter. Mauck scored on a four-yard keeper early in the second quarter and made it 24-0 with a 48-yard scoring pass to Michael Clayton with 9:32 to go before halftime.
"I was pleased with the way Matt played," Saban said. "He was 9-for-10. When a guy comes on the trip and gets to play in the game, I expect them all to play well."
Louisiana State (2-0) had a 52-0 lead before Arizona (0-2) spoiled the shutout bid with 10:42 remaining, when Zeonte Sherman returned a fumble one yard for a touchdown.
Marcus Randall took over Mauck completed 10-of-15 passes for 162 yards. Clayton caught six passes for 109 yards as the Tigers totaled 481 yards, including 299 in the air.
"I think everything worked out that we tried," Mauck said. "Things we didn't execute well last week, we did well this week. If we keep executing as good as we are supposed to, we should be able to play this well every week."
Off to its sixth 2-0 start in seven years, LSU won its first non-conference road game since defeating Tulane in 1991.
Arizona's Nic Costa was sacked just once but was under constant pressure and completed just 3-of-11 passes for 21 yards.
"They seemed to have two or three guys on every one of our receivers," Costa said. "I'm shocked. Going in, we had a good game plan and we knew they were ranked 13th in the country, but we were confident. They outhit us and outhustled us."
LSU set the tone immediately, going 80 yards in 15 plays on its opening drive. Ryan Gaudet kicked a 47-yard field goal and Addai added his second TD of the quarter with 4:23 left for a 17-0 cushion.
"When we jump on somebody and get ahead early, that affects both sides emotionally," Saban said.
Randall came in midway through the second quarter and threw a 55-yard touchdown pass to Deveney Henderson with 5:20 left in the first half. The Tigers had a 38-0 lead at intermission.
Shyron Carey ran one yard for a TD in the third quarter and Justin Vincent also scored on a one-year run 3:11 into the fourth for a 52-0 cushion.