PROVO, Utah (Ticker) -- Brigham Young became the latest team to discover there is no answer for Reggie Bush.
A sensational sophomore, Bush had 208 all-purpose yards and two touchdowns as top-ranked Southern California ran its winning streak to 12 games with a 42-10 romp over the Cougars.
Bush ran for a career-high 124 yards and a touchdown on just 14 carries and scored on a screen pass for USC (3-0), which was playing in the Beehive State for the first time since a 51-0 trouncing of Utah in 1917.
The Trojans trailed, 3-0, before Bush caught a screen pass from Matt Leinart in the middle of the field, cut left and scampered 21 yards into the end zone with 8 1/2 minutes left in the second quarter.
USC broke open the game just before halftime. Bush scored his sixth TD of the season on a 66-yard run down the right sideline with 2:03 left.
After Trojans linebacker Lofa Tatupu recovered a fumble by Cougars quarterback John Beck on the next scrimmage play, Leinart tossed a 15-yard TD to true freshman Dwayne Jarrett in the middle of the end zone.
The score was 21-10 before USC tacked on three fourth-quarter touchdowns.
LenDale White added 110 yards and a late touchdown on 17 carries for the Trojans, who outgained the Cougars (1-2) on the ground, 291-27, and 527-221 overall.
"I loved the way the offensive line played," USC coach Peter Carroll said. "We really thought we were going to come in here and run the football tonight."
Leinart, a leading Heisman Trophy candidate, completed 22-of-35 passes for 236 yards, two TDs and one interception.
"You can see why they're the No. 1 team in the country," BYU coach Gary Crowton said. "Our defense did really well at times, but with them having so many weapons it was hard to maintain our momentum."
Beck completed 18-of-34 passes for 194 yards, one TD and three interceptions. "I felt like it was good for Beck to play the whole game and watch him develop," Crowton said. "I think it's only the second time in his career that he's had a whole game under his belt. He'll continue to develop and get better and better."
Trojans offensive coordinator Norm Chow spent 27 years as an assistant at BYU between 1973-99.