Updated: Saturday, September 25, 2004 8:39 AM EDT
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Green Bay (1-1) at Indianapolis (1-1) Sunday, 4:15 pm EDT

INDIANAPOLIS (Ticker) -- Peyton Manning and Brett Favre duel for the second and perhaps last time Sunday when the Indianapolis Colts stage their home opener against the Green Bay Packers in an interconference matchup.

Of course, the Pro Bowl quarterbacks wouldn't mind setting a date for February 6 in Jacksonville for Super Bowl XXXIX.

The first meeting was quite a memorable one at Lambeau Field on November 19, 2001. Favre, a three-time Most Valuable Player from 1995-97, completed 23-of-36 passes for 301 yards and two touchdowns to lead the Packers to a 26-24 victory. Manning threw for 294 yards and three scores.

Both quarterbacks stand for durability and excellence. Favre, who turns 35 in October, ranks in the NFL's top five in four major categories: second in touchdowns (348), fourth in completions (3,999), fifth in attempts (6,528) and fifth in yards (46,041).

With a career record of 126-65, Favre holds the fourth-highest winning percentage among starting quarterbacks who began their careers since the 1970 league merger.

And then of course, there's the streak. Favre has started 191 consecutive games, 210 including playoffs, which is an NFL record for a quarterback.

Manning will be starting his 99th consecutive game on Sunday, the fourth-longest streak by a quarterback in NFL history and the longest to start a career. Manning ranks behind Favre, Ron Jaworski (116, 1977-84) and Joe Ferguson (107, 1977-84) The co-Most Valuable Player in 2003, Manning reached 25,000 passing yards in 97 games, second to Dan Marino at 92. Favre was tied for third fastest to 25,000 in 107 games.

Manning is the only NFL player to throw for more than 3,000 yards in each of his first six seasons. He is also the only player to throw for more than 4,000 yards in five consecutive seasons (1999-2003). Favre had three 4,000-yard seasons (1995, 1998-99).

After opening the season against two-time Super Bowl Most Valuable Player Tom Brady and fellow MVP Steve McNair in 2003, Manning now draws Favre, who threw for 252 yards, but was intercepted twice in last week's 21-10 loss to Chicago.

Manning has completed 40-of-62 passes for 510 yards and four touchdowns with one interception in Indianapolis' first two games. He threw for 254 yards and two touchdowns in the Colts' 31-17 victory at Tennessee last week.

But Manning may not have Edgerrin James in his backfield this weekend. James suffered a hamstring injury after breaking off a 30-yard touchdown run in the fourth quarter last week. He has rushed for 266 yards on 51 carries in Indianapolis' first two games.

With James Lee making his first start at defensive tackle last week for an injured Grady Jackson (knee), the Packers yielded 152 yards on the ground to Chicago's Thomas Jones .

Favre will have Ahman Green , who has gained 247 yards on 57 carries in Green Bay's first two games. But Green committed a key fumble in last week's loss, getting stripped of the ball at the Chicago 2 by Brian Urlacher and safety Mike Brown returned it 95 yards for a touchdown.

The Colts also had trouble defending the run, giving up 152 yards on the ground to Tennessee's Chris Brown last week.

Matchup to watch: Packers left tackle Chad Clifton faces Colts right end Dwight Freeney .

Series: Green Bay leads the series, 20-19-1, although the teams have met just three times in the last 13 years.

Next week: Green Bay hosts the New York Giants , October 3 Indianapolis visits Jacksonville, October 3

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