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INDIANAPOLIS (Ticker) -- After the NFL didn't let Peyton Manning wear high tops, the Miami Dolphins had him feeling pretty low.

Manning was intercepted three times in an awful first half and had a last-gasp pass knocked away as the Dolphins held on for a 21-13 victory over the Indianapolis Colts .

Ricky Williams rushed for 132 yards and Jay Fiedler threw for two touchdowns and ran for another for the Dolphins (2-0), who have won five straight visits to the RCA Dome.

But Miami won this game with defense, frustrating Manning in the first half, making a goal-line stand in the third quarter and stopping Indianapolis inside the 10 four times, including the final drive.

"The Colts are going to be one of the best offenses again in the league and to hold them to 13 points at home is a great accomplishment for our defense," Dolphins coach Dave Wannstedt said. "Don't underestimate what that means to us."

Upon hearing of former Colts great Johnny Unitas' death, Manning - a quarterback's son and a true student of football history - expressed a desire to wear the black high-top cleats popularized by the Hall of Famer. But the NFL nixed the idea, threatening a $25,000 fine if Manning did not comply.

After the first half, Manning needed work boots instead of cleats. He dug the Colts a 21-3 hole with three interceptions, including one deep in Miami territory late in the second quarter.

"It's tough when you spot a good team as much as we spotted them and made the kind of errors that allowed them to get ahead," Colts coach Tony Dungy said.

The Colts (1-1) closed to 21-13 when Manning took over on his 16-yard line with 2:15 to go. He move the team downfield with the help of Edgerrin James , who ran three times for 30 yards on the drive. But the Dolphins kept James and his teammates inbounds, burning the clock.

"I think it was OK, really," Manning said. "With the coverages they were in, all the openings were in the middle of the field. There were a few cases of people just trying to get as much yardage as they could and not getting out of bounds."

Manning's 26-yard sideline pass to Troy Walters moved Indianapolis to the 12 with 19 seconds left, but Qadry Ismail was tackled inbounds after a six-yard catch. Manning had to spike the ball with two seconds left, and his end-zone pass over the middle to Ismail was easily batted away by safety Brock Marion .

Williams carried 24 times as he became the first Dolphin to put together 100-yard rushing games since Bernie Parmalee in 1994. He also caught two passes for 62 yards and a touchdown. Fiedler completed 13-of-18 passes for 187 yards.

"I've been giving Norv (offensive coordinator Norv Turner) a hard time about not throwing me the ball," Williams said. "I had 60 catches last year (with New Orleans)."

Manning was 26-of-45 for 289 yards and a TD to Marvin Harrison , who caught 11 passes for 144 yards. James carried 30 times for 138 yards but was stopped four straight times from the 2 in the third quarter.

An interception and 20-yard return by David Macklin , an unnecessary roughness penalty on Miami and a 33-yard pass from Manning to Harrison moved the Colts to the 2. James gained one yard on three carries into the line before trying to go left and getting dragged down for a loss by Tommy Hendricks .

"It was very frustrating," Manning said. "You kind of get stuck in that run mode because we gained a little each play until fourth down."

"I just tried to hit it up there, close the gap," Dolphins middle linebacker Zach Thomas said. "We've been playing good goal line and I'm glad we kept it going."

Manning engineered three long drives in the fourth quarter. The first was 80 yards and capped by his 16-yard TD pass to Harrison. The second was 71 yards and stalled at the 7 before Mike Vanderjagt kicked a 23-yard field goal with 2:54 to go. And the third was 78 yards and ended with Marion's knockdown.

"That was the difference in the game," Dungy said. "We went up and down the field as much as they did. They scored touchdowns with theirs. We didn't score at all at times, had to settle for field goals."

The Dolphins scored on their first two possessions, with Derrick Rodgers ' interception in between. Fiedler bootlegged in from a yard out before throwing a nine-yard TD pass to Rob Konrad for a 14-0 lead late in the first quarter.

In the second quarter, Vanderjagt kicked a 25-yard field goal after a drive died at the 7. Fiedler immediately responded with a 52-yard screen pass to Williams before finding the big tailback with a 10-yard TD toss and a 21-3 lead with 1:53 left.

"Even when they put eight in the box, we still ran the ball," Williams said. "In that situation, they really can't win. They bit on a lot of fakes because they had to respect the running game."

Patrick Surtain picked off Manning in the end zone in the final minute of the first half.