Curtis Brown scored 6:13 into overtime as the Sabres grabbed a 4-3 victory over the Flyers and a commanding three games to one lead in their Eastern Conference quarterfinal series.
Skating from behind the net, Brown curled into the slot before flipping a wrist shot past goaltender Roman Cechmanek into the top right corner of the net.
"We were battling along the wall, I was walking out just trying to find some open space," Brown said. "When it shut down there early, I just hung on to it. Luckily things opened up a bit. I shot it up top and found a spot for us."
Flyers coach Bill Barber was more concerned with how the play was defended.
"(Michal Sykora's) got to stay on his feet and (Simon) Gagne's got to stay on his guy," Barber said. "You can't let a guy walk out through the seams. You can't let guys get a wraparound."
It was the second victory in overtime in the series for Buffalo, which also posted a 4-3 victory in Game Two. The Sabres have won six of the last seven overtime games between the teams in the postseason.
"Play against (Keith) Primeau, (Mark) Recchi and (Gagne), those are three of the fastest guys in the league on one line," Sabres coach Lindy Ruff said. "That is no easy task."
Dan McGillis scored a shorthanded goal with 9:44 left in regulation for Philadelphia to send the game into overtime.
Chris Gratton had scored at 15:30 of the second for the Sabres, snapping a 2-2 tie. The former Flyers center has three goals and two assists in the series, matching his career point total from 16 previous postseason games.
"We wanted to get the puck up a little bit," said Gratton, whose Buffalo teammates also shot high to beat Cechmanek. "I just wanted to get it off quick and fortunately it got in the air for me."
The Flyers have won five of six all-time playoff series from the Sabres. However, the Flyers have lost all 10 of their postseason series when losing Game Four to fall behind three games to one.
"It's been done before and New Jersey did it to us last year," said Flyers defenseman Andy Delmore, who was minus-2 one night after scoring the game-winner. "It's not like we're down 3-0, we've got one. We're going to have to be ready to go the next game."
Cechmanek, who made 31 saves in the losing effort, had smothered Brown's pair of point-blank shots 3:55 into the extra session before being beaten for the game-winner. The Sabres' center tallied seven goals in Buffalo's 1999 Stanley Cup finals run.
Dominik Hasek may not have been "The Dominator" for Buffalo Tuesday night, uncharacteristically letting the Flyers come from behind twice. However, the five-time Vezina Trophy winner stopped 30 shots to post his 33rd career playoff win.
Hasek lost his stick while stopping Paul Ranheim's effort at the right goalpost seconds before McGillis' equalizer.
Ranheim fed McGillis just inside the blue line. The Buffalo goaltender failed to get his blocker to the ice in time.
"Before I grabbed the stick, he was shooting from the blue line and the puck went through my five-hole," Hasek said. "It wasn't a hard shot."
A pair of defensive blunders by the Flyers allowed Miroslav Satan and Donald Audette to score during a 50-second span. That gave the Sabres a 2-0 lead just 2:18 into the contest, respresenting the first two-goal advantage for either team in this series.
"I don't know where their defense went, but all of a sudden there was two guys in front of Cechmanek," Satan said of his second goal of the series. "I just grabbed the rebound and put it upstairs."
But the Flyers fought back as Daymond Langkow scored late in the first and Gagne tallied early in the second period to tie it at 2-2.
Game Five is in Philadelphia on Thursday.