Grizzlies defeat Spurs
2011 (Western Conference first round)
The Spurs were the West's best regular-season team with a 61-21 record, but a late-season slide (they lost eight of their last 12 games) continued through the postseason and they fell to the 46-win and eighth-seeded Grizzlies in six games. It marked only the second time in NBA history that a No. 1 seed had lost to a No. 8 seed in a best-of-seven series.