Shaquille O'Neal vs. Kobe Bryant
After winning three consecutive NBA championships from 2000 to '02, Shaq and Kobe became basketball's version of Ike and Tina. Before the '03-04 season, Shaq took a shot at Kobe by questioning his importance to the team, and Kobe fired back by criticizing the center for not taking responsibility for losses. After the Lakers lost in the NBA finals, Shaq landed in Miami, and over the next two years the two took shots at each other through the media, with their head-to-head matchups producing unprecedented hype. The feud ended in 2006, however, when the two reconciled at the All-Star Game.