Andy Reid and Donovan McNabb, Eagles
The Eagles and Andy Reid made Donovan McNabb the No. 2 overall pick in the 1999 draft and were rewarded with one of the winningest decades in NFL history. Over the next 10 years, Reid and McNabb combined to win 92 games, but are often remembered for their on-again, off-again relationship. The tandem reached its peak in 2004 when the Eagles advanced to the Super Bowl. But Philly lost to New England in the title game and never made it back. After numerous controversies, Reid and McNabb parted ways in 2010 following the reemergence of Michael Vick.