Giants vs. 49ers
Justin Smith vs. David Diehl
Smith has been a monster all year, registering seven-and-a-half sacks and 58 tackles for San Francisco's strong defense. The 11th-year defensive end continued his strong play on Saturday, sacking Drew Brees once in the 49ers' big win. New York left tackle David Diehl will have the tough job of keeping Smith out of the backfield this weekend.