Colts' WR Donnie Avery (vs. Bills)
The Bills secondary had a great week against the Dolphins, but Ryan Tannehill is no Andrew Luck, so the receiving yards will be there for the Colts. Reggie Wayne is always option No. 1, but with two 100-yard games in his last three, T.Y. Hilton is likely to get special attention from the Bills. That will leave Avery to roam in space and do what everyone besides Miami has been able to do this year: get behind Buffalo's secondary.