Posted: Fri December 21, 2012 3:04PM; Updated: Fri December 21, 2012 3:04PM
Andrew Perloff
Andrew Perloff>INSIDE THE NFL

Bet On It: Week 16 predictions

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Eli Manning
In need of a win to keep their playoff hopes alive, Eli Manning and the Giants might have found the perfect foe in the struggling Ravens.
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Last Week 4-6; Season record: 59-81

This is the time of year you have to guess who's tuning out the coaching staff and who's playing for a contract. If I don't come up with some victories the last two weeks, I could be playing for a contract, so I've put in maximum effort this week:

1. Giants defeat the Ravens

The Giants typically respond when they have their backs against the wall. They're a bit banged up on the O-line and we don't know if running back Ahmad Bradshaw can play yet, but they'll find a way. Also, decent teams tend to play well after an embarrassing blowout. The Giants lost 34-0 to the Falcons last week. Then again, the Ravens lost 34-17 to the Broncos. Their offense is reeling despite changing coordinators, so it's hard to call Baltimore, losers of three straight, a decent team right now.

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2. Steelers beat the Bengals

Pittsburgh beat Cincy 24-17 in Week 7 when it was dealing with a rash of injuries. The Bengals have gone on a run since then, but they've beaten some bad teams. Last week's win over Philly was deceptive because the Eagles handed them the win. Cincinnati follows the same pattern almost every week -- get the lead early, make a series of mistakes and lose it and then either come back or lose. In this high-stakes contest, the Bengals won't be able to recover from their mistakes.

3. Seahawks quarterback Russell Wilson and 49ers quarterback Colin Kaepernick will combine for less than 500 passing yards

As well as Wilson and Kaepernick have played lately, this will be a different kind of game for both quarterbacks. San Francisco and Seattle rank No. 2 and No. 3, respectively, in defense, and this contest will be all about ball control. Both quarterbacks may have to try to win this game with their legs and not their arms.

4. Panthers quarterback Cam Newton finishes with a QB Rating over 95 rating against the Raiders

Newton has gone five straight games without throwing an interception and is making everyone forget about his first-half struggles. The Raiders actually have the sixth-ranked pass defense -- in part because they're so easy to run on. But Oakland has only 10 picks on the year, and Newton will continue to be careful as he continues his productive run.

5. Bears quarterback Jay Cutler posts a QB Rating under a 90 rating against the Cardinals

Lost in their disaster of a season is how well Arizona's defense can play. The Cardinals beat the Lions 38-10 last week with almost no help from the offense. Cutler and the Bears' offense are out of sync. Chicago also has a tough defense and should win, but it won't be because of Cutler.

6. Cowboys quarterback Tony Romo throws for over 300 yards

Romo is hot, and the Cowboys have everything on the line against the Saints. New Orleans' defense typically doesn't put up much of a fight on the road and will have trouble handling Dallas' receivers.

7. Rams receiver Danny Amendola has at least seven catches

St. Louis' top wideout appears to finally be healthy and will be the main target against Tampa Bay's 32nd-ranked pass defense. We saw last week against Minnesota that the Rams aren't afraid to go pass-happy when necessary.

8. Patriots tight end Aaron Hernandez has at least seven catches

With Rob Gronkowski out, Hernandez has been Tom Brady's main target. He has 26 catches for 243 yards and three touchdowns over the last three weeks. The Pats might get up early and not need to pass against Jacksonville, but Hernandez is such a big part of the passing game right now that he could get his production out of the way early.

9. Jaguars quarterback Chad Henne throws for at least 225 yards against the Patriots

Henne has struggled the last few games, but he hopes to show enough to earn a chance to compete for a starting job next season. He had some strong efforts against the Pats when he was in Miami and he'll have a good opportunity to toss the rock around in Week 16 against New England's 29th-ranked pass defense.

10. The Broncos win the turnover battle against the Browns

Cleveland quarterback Brandon Weeden threw two picks against the Redskins last week and he faces a much tougher defense in Denver. He needs to finish well to keep the Browns from going after another quarterback in the offseason. Cleveland will have a hard time blocking the Broncos' Von Miller, and Weeden will make mistakes under the pressure.

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