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Volunteers needed
Australia trying to develop tests for erythropoietin
Posted: Friday January 07, 2000 10:31 AM
SYDNEY, Australia (AP) -- The Australian Institute of Sport (AIS)
is seeking volunteers to take the banned performance-enhancing drug
erythropoietin (EPO) as it tries to develop test for it ahead of
the Sydney Olympics.
In collaboration with the Australian Sports Drug Testing
Laboratory, the AIS is calling for 120 fit and frequent
sport-playing men and women aged between 18 and 35 to take EPO for
14 weeks and be monitored to determine the effects of the synthetic
hormone on athletes.
EPO boosts performance by increasing the number of red blood
cells, which enables the blood to carry oxygen.
The call for volunteers follows a decision by the International
Olympic Committee (IOC) late last year to provide about a million
dollars towards validating a method of testing for the drug, which
is undetectable in urine samples.
The Australian government has also pledged the same amount to
the program.
EPO has been linked to the deaths of a number of European
cyclists as it thickens the blood and causes heart failure.
Dr. Ross Smith, director of AIS Sport Sciences, said the
volunteers will be at no risk during the trial.
"[Small doses] could see minor ailments like hypertension or
flu-like symptoms, but if someone takes EPO in an unsupervised
manner then it could lead to death," Smith said.
"EPO clogs up the system, the blood becomes very thick and
can't be pumped around by the heart.
"But this [trial] has been through out ethics committee, the
dose which has been decided upon is a very low level, and if there
is any doubt that will be identified during the initial medical
screening program, as well as through any monitoring that we do."
Smith said the dosage to be given to volunteers is well below
amounts taken by people who have a genuine medical condition which
requires EPO.
The AIS is hoping a broad cross-section of the community
representing a range of ethnic groups will participate in the
study.
Copyright 2003 Associated Press. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.
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