In the league's 16th season, the hottest action will be in the soccer-mad Pacific Northwest, where expansion Portland and Vancouver join wildly popular Seattle; in the end, though, it should be L.A. making the biggest news. Here's SI's take on how the standings will break down.
1. NEW YORK
F Thierry Henry is ready to improve on his injury-plagued '10 season, and F Juan Agudelo, an 18-year-old rising star, will shine as well.
2. KANSAS CITY
F Teal Bunbury and F Omar Bravo are two of the league's most exciting players, and newly dubbed Sporting K.C. is on the upswing.
The Dynamo should rebound from a poor '10 with the return to health of F Brian Ching and M Geoff Cameron.
4. D.C. UNITED
It can only get better for United, which made positive additions in F Charlie Davies, M Dax McCarty and D Perry Kitchen.