Marques COLSTON SAINTS
COLSTON HAD surgery on his "good" (right) knee in January, leaving him with the worst knees this side of Frank Gore. He can come back, but he probably can't come back to the WR1 level.
Michael CRABTREE 49ERS
CRABTREE IS out with a foot injury at least through August and may miss the start of the season. San Francisco moved quickly to replace Crabtree with Braylon Edwards, who immediately becomes the team's most proven wideout.
Percy HARVIN VIKINGS
THE VIKINGS have tried everything to help control Harvin's history of migraines, and all reports now say he hasn't had any since January. Harvin's owners hope they don't return. Otherwise he will cause headaches every Sunday morning.
Emmanuel SANDERS STEELERS
POISED TO take over as the team's No. 2 receiver, Sanders has undergone three surgeries—one on his right foot and two on his left—since the Super Bowl. His return for Week 1 is in doubt.